Data Mining Using Relational Database Management Systems

Software packages providing a whole set of data mining and machine learning algorithms are attractive because they allow experimentation with many kinds of algorithms in an easy setup. However, these packages are often based on main-memory data structures, limiting the amount of data they can handle. In this paper we use a relational database as secondary storage in order to eliminate this limitation. Unlike existing approaches, which often focus on optimizing a single algorithm to work with a database backend, we propose a general approach, which provides a database interface for several algorithms at once. We have taken a popular machine learning software package, Weka, and added a relational storage manager as back-tier to the system. The extension is transparent to the algorithms implemented in Weka, since it is hidden behind Weka’s standard main-memory data structure interface. Furthermore, some general mining tasks are transfered into the database system to speed up execution. We tested the extended system, refered to as WekaDB, and our results show that it achieves a much higher scalability than Weka, while providing the same output and maintaining good computation time

Review of Individual differences in language learning: A complex systems theory perspective; Authors: Carol Griffiths, Adem Soruç; Publisher: Palgrave Macmillan, 2020; ISBN: 978-3-030-52900-0; Pages: 220

Book Review: Individual differences in language learning: A complex systems theory perspective. Authors: Carol Griffiths, Adem Soruç. Publisher: Palgrave Macmillan, 2020. ISBN: 978-3-030-52900-0. Pages: 220

Machine Directional Register System Modeling for Shaft-Less Drive Gravure Printing Machines

In the latest type of gravure printing machines referred to as the shaft-less drive system, each gravure printing roller is driven by an individual servo motor, and all motors are electrically synchronized. The register error is regulated by a speed difference between the adjacent printing rollers. In order to improve the control accuracy of register system, an accurate mathematical model of the register system should be investigated for the latest machines. Therefore, the mathematical model of the machine directional register (MDR) system is studied for the multicolor gravure printing machines in this paper. According to the definition of the MDR error, the model is derived, and then it is validated by the numerical simulation and experiments carried out in the experimental setup of the four-color gravure printing machines. The results show that the established MDR system model is accurate and reliable

A plane linkage and its tessellation for deployable structure

Deployable structures are widely used in space applications such as solar arrays and antennas. Recently, inspired by origami, more deployable structures have been developed. This paper outlined a novel design scheme for deployable structures by taking a plane linkage as an origami unit with a large deployable ratio. The mountain and valley (M-V) crease assignment and kinematics of the plane linkage were analyzed. Physical interference in the folding progress was discovered geometrically and resolved by the split-vertex technique. Finally, tessellation of the derived pattern was successfully used to create a large-deployable-ratio structure, which was found to exhibit considerable potential in future space applications

Excess caffeine exposure impairs eye development during chick embryogenesis

Caffeine has been an integral component of our diet and medicines for centuries. It is now known that over consumption of caffeine has detrimental effects on our health, and also disrupts normal foetal development in pregnant mothers. In this study, we investigated the potential teratogenic effect of caffeine over-exposure on eye development in the early chick embryo. Firstly, we demonstrated that caffeine exposure caused chick embryos to develop asymmetrical microphthalmia and induced the orbital bone to develop abnormally. Secondly, caffeine exposure perturbed Pax6 expression in the retina of the developing eye. In addition, it perturbed the migration of HNK-1(+) cranial neural crest cells. Pax6 is an important gene that regulates eye development, so altering the expression of this gene might be the cause for the abnormal eye development. Thirdly, we found that reactive oxygen species (ROS) production was significantly increased in eye tissues following caffeine treatment, and that the addition of anti-oxidant vitamin C could rescue the eyes from developing abnormally in the presence of caffeine. This suggests that excess ROS induced by caffeine is one of the mechanisms involved in the teratogenic alterations observed in the eye during embryogenesis. In sum, our experiments in the chick embryo demonstrated that caffeine is a potential teratogen. It causes asymmetrical microphthalmia to develop by increasing ROS production and perturbs Pax6 expression

Research and Simulation of DC Microgrid Three-Phase AC-DC Converter Control Strategy Based on Double Loop

The new voltage and current double loop control strategy is proposed to solve the DC microgrid bus voltage fluctuation caused by loads fluctuation, parameters perturbation and unbalanced three-phase power supply. Firstly, the dq axis mathematical model of three-phase AC-DC bidirectional converter in DC microgrid is analyzed and established, and then the controllers are designed according to the dq axis mathematical model. The outer loop is a voltage loop based on variable gain linear extended state observer (VGLESO) and sliding mode theory. VGLESO can not only effectively overcome the problem of peak output of traditional high-gain LESO in the initial stage of operation, and ensure that the system has good startup characteristics, but also quickly track and compensate the total disturbance of the system without additional current sensors. The inner loop is a current loop based on adaptive PI, which can eliminate the influence of system parameters perturbation on bus voltage and improve the system\u27s adaptability. Under the action of the inner and outer loops, the system has good dynamic and static characteristics. Finally, the feasibility and correctness of the control strategy are verified by Matlab/Simulink

Cross-modal and Cross-domain Knowledge Transfer for Label-free 3D Segmentation

Current state-of-the-art point cloud-based perception methods usually rely on large-scale labeled data, which requires expensive manual annotations. A natural option is to explore the unsupervised methodology for 3D perception tasks. However, such methods often face substantial performance-drop difficulties. Fortunately, we found that there exist amounts of image-based datasets and an alternative can be proposed, i.e., transferring the knowledge in the 2D images to 3D point clouds. Specifically, we propose a novel approach for the challenging cross-modal and cross-domain adaptation task by fully exploring the relationship between images and point clouds and designing effective feature alignment strategies. Without any 3D labels, our method achieves state-of-the-art performance for 3D point cloud semantic segmentation on SemanticKITTI by using the knowledge of KITTI360 and GTA5, compared to existing unsupervised and weakly-supervised baselines.Comment: 12 pages,4 figures,accepte

Effects of High Salt-Exposure on the Development of Retina and Lens in 5.5-Day Chick Embryo

Background/Aims: Excess maternal salt intake during pregnancy may alter fetal development. However, our knowledge on how an increased salt intake during pregnancy influences fetal eye development is limited. In this study, we investigated the effects of high-salt treatment on the developing eyes in chick embryos, especially focusing on the development of the retina and the lens. Methods: 5.5-day chick embryos were exposed to 280mosm/l (n=17), or 300mosm/l (n=16) NaCl. The treated embryos were then incubated for 96 hours before they were fixed with 4% paraformaldehyde for H&E staining, whole-mount embryo immunostaining and TUNEL staining. BrdU and PH3 incorporation experiments were performed on the chick embryos after high-salt treatment. RT-PCR analyses were conducted from chick retina tissues. Results: We demonstrated that high-salt treatment altered the size of eyes in chick embryos, induced malformation of the eyes and impaired the development of the lens and the retina. We found an impaired expression of Paired box 6 (PAX6) and neuronal cells in the developing retina as revealed by neurofilament immunofluorescent staining. There was a reduction in the number of BrdU-positive cells and PH3-positive cells in the retina, indicating an impaired cell proliferation with high-salt treatment. High-salt treatment also resulted in an increased number of TUNEL-positive cells in the retina, indicating a higher amount of cell death. RT-PCR data displayed that the expression of the pro-apoptotic molecule nerve growth factor (NGF) in chick retina was increased and CyclinD1 was reduced with high-salt treatment. The size of the lens was reduced and Pax6 expression in the lens was significantly inhibited. High salt-treatment was detrimental to the migration of neural crest cells. Conclusion: Taken together, our study demonstrated that high-salt exposure of 5.5-day chick embryos led to an impairment of retina and lens development, possibly through interfering with Pax6 expression

Proper autophagy is indispensable for angiogenesis during chick embryo development

People have known that autophagy plays a very important role in many physiological and pathological events. But autophagy role on embryonic angiogenesis still remains obscure. In this study, we demonstrated that Atg7, Atg8 and Beclin1 were expressed in the plexus vessels of angiogenesis at chick yolk sac membrane and chorioallantoic membrane. Interfering with autophagy with autophagy inducer or inhibitor could restrict the angiogenesis in vivo, which might be driven by the disorder of angiogenesis-related gene expressions, and also lead to embryonic hemorrhage, which was due to imperfection of endothelial cell-cell junctions including abnormal expressions of tight junction, adheren junction and desmosome genes. Using HUVECs, we revealed that cell viability and migration ability changed with the alteration of cell autophagy exposed to RAPA or 3-MA. Interestingly, tube formation assay showed that HUVECs ability of tube formation altered with the change of Atg5, Atg7 and Atg8 manipulated by the transfection of their corresponding siRNA or plasmids. Moreover, the F-actin labeled cell polarity lost and β-catenin absence in RAPA-treated cell membrane implied intracellular cytoskeleton alteration was induced by autophagy level. Taken together, our current experimental data reveal that autophagy is really involved in regulating angiogenesis during embryo development